BSF-466895
BSF-466895(A-422885.66) is a Tie2 inhibitor with an IC50 of 5 nM and it can also inhibit Tie1.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 262442-90-0
- Formel: C29H32Cl2FN7O2S
- Molecular Weight:632.58
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
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Tie2 5 nM (IC50) |
Chemical Information
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CAS. Nr. 262442-90-0
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Molecular Weight 632.58
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Formel C29H32Cl2FN7O2S
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SMILES
O=S(C1=CC=CC(Cl)=C1Cl)(NC2=CC=C(C3=CN([C@H]4CC[C@H](N5CCN(C)CC5)CC4)C6=NC=NC(N)=C63)C=C2F)=O
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Synonyms
A-422885.66
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
[1]. Jerry Adams, et al. A strategy for the design of multiplex inhibitors for kinase-mediated signalling in angiogenesis. Curr Opin Chem Biol. 2002 Aug;6(4):486-92. [Content Brief]
[2]. Dieter Marmé, et al. The impact of anti-angiogenic agents on cancer therapy. J Cancer Res Clin Oncol. 2003 Nov;129(11):607-20. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
BSF-466895 Related Classifications
HY-15973 Related Classifications
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