Catalponol
Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells.
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- CAS. Nr.: 34168-56-4
- Formel: C15H18O2
- Molecular Weight:230.30
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
In RAW 264.7 macrophage cells, Catalponol exhibits potent inhibitory effects with an IC50 value of 9.8 μM for inhibiting LPS-induced NO production[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 34168-56-4
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Molecular Weight 230.30
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Formel C15H18O2
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SMILES
O=C1C2=CC=CC=C2[C@@H](O)C[C@H]1C/C=C(C)/C
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75. [Content Brief]
[2]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Catalponol Related Classifications
HY-N3550 Related Classifications
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