Cinnamic acid-d6
Based on 1 Customer Validation
Cinnamic acid-d6 is the deuterium labeled Cinnamic acid. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.9%
- CAS. Nr.: 91453-04-2
- Formel: C9H2D6O2
- Molecular Weight:154.20
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 91453-04-2
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Unlabeled Cas 621-82-9
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Appearance Solid
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Molecular Weight 154.20
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Formel C9H2D6O2
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Color White to off-white
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SMILES
OC(/C=C([2H])/C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O
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Synonyms
3-Phenylacrylic acid-d6; β-Phenylacrylic acid-d6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 250 mg/mL (1621.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Liu L, et al. Cinnamic acid: a natural product with potential use in cancer intervention. Int J Cancer. 1995 Jul 28;62(3):345-50. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4851 mL | 32.4254 mL | 64.8508 mL | 162.1271 mL |
| 5 mM | 1.2970 mL | 6.4851 mL | 12.9702 mL | 32.4254 mL | |
| 10 mM | 0.6485 mL | 3.2425 mL | 6.4851 mL | 16.2127 mL | |
| 15 mM | 0.4323 mL | 2.1617 mL | 4.3234 mL | 10.8085 mL | |
| 20 mM | 0.3243 mL | 1.6213 mL | 3.2425 mL | 8.1064 mL | |
| 25 mM | 0.2594 mL | 1.2970 mL | 2.5940 mL | 6.4851 mL | |
| 30 mM | 0.2162 mL | 1.0808 mL | 2.1617 mL | 5.4042 mL | |
| 40 mM | 0.1621 mL | 0.8106 mL | 1.6213 mL | 4.0532 mL | |
| 50 mM | 0.1297 mL | 0.6485 mL | 1.2970 mL | 3.2425 mL | |
| 60 mM | 0.1081 mL | 0.5404 mL | 1.0808 mL | 2.7021 mL | |
| 80 mM | 0.0811 mL | 0.4053 mL | 0.8106 mL | 2.0266 mL | |
| 100 mM | 0.0649 mL | 0.3243 mL | 0.6485 mL | 1.6213 mL |
Cinnamic acid-d6 Related Classifications
HY-N0610AS Related Classifications
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