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Delpacibart

(Synonyms: AOC-1001 Antibody; AOC-1044 Antibody)
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Delpacibart is a humanized IgG1κ monoclonal antibody targeting the transferrin receptor TFRC. Delpacibart can be conjugated with the phosphorodiamidate morpholino oligonucleotide (PMO) Zotadirsen (HY-177972), which targets exon 44 of the dystrophin gene, to synthesize the antibody-oligonucleotide conjugate (AOC) Delpacibart zotadirsen (HY-177564). Delpacibart is suitable for use in Duchenne muscular dystrophy (DMD44) research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 98.06%
  • CAS. Nr.: 2653183-66-3
  • Molecular Weight:144.44 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Delpacibart
  • Experimental Validation Results for Delpacibart
  • Experimental Validation Results for Delpacibart
  • Delpacibart Chemical Structure
    Delpacibart Chemical Structure
CAS. Nr.: 2653183-66-3
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Delpacibart Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized TFRC Protein, Human can bind Delpacibart. The EC50 for this effect is 14.67 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 FaDu cells with Delpacibart (HY-P990051, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 (L234A/L235A) kappa (HY-P991027, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Delpacibart Chemical Structure
    1/16
  • Delpacibart
  • Immobilized TFRC Protein, Human can bind Delpacibart. The EC50 for this effect is 14.67 ng/mL.
  • Flow cytometric analysis of 1X106 FaDu cells with Delpacibart (HY-P990051, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 (L234A/L235A) kappa (HY-P991027, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).