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Efercoleukin alfa

(Synonyms: XTX-202)
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Efercoleukin alfa (XTX-202) is an IL-2 Rβ-biased IL-2 which has a masking domain to prevent IL-2 activity in non-tumor regions along with a half-life extension domain. The masking domain is cleaved by matrix metalloproteases (MMP) in the TME, leading to the release of the IL-2 R agonist. Efercoleukin alfa shows potential immunoregulatory and antineoplastic activities.

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  • Reinheit: 99.9%
  • CAS. Nr.: 2760549-52-6
  • Molecular Weight:93.436 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Efercoleukin alfa
  • Experimental Validation Results for Efercoleukin alfa
  • Efercoleukin alfa Chemical Structure
    Efercoleukin alfa Chemical Structure
CAS. Nr.: 2760549-52-6
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    FPIA-FC_[PROTEIN]3

  • 1/16

    Measured in a cell proliferation assay using CTLL-2 cell. The ED50 for this effect is 113 ng/mL, corresponding to a specific activity is 8849.558 units/mg.

  • Efercoleukin alfa Chemical Structure
    1/16
  • Efercoleukin alfa
  • Measured in a cell proliferation assay using CTLL-2 cell. The ED50 for this effect is 113 ng/mL, corresponding to a specific activity is 8849.558 units/mg.
  • FPIA-FC_[PROTEIN]3