Enniatin A
Enniatin A is a Fusarium mycotoxin. Enniatin A inhibits acyl-CoA: cholesterol acyltransferase (ACAT) activity with an IC50 of 22 μM in an enzyme assay using rat liver microsomes.
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- CAS. Nr.: 2503-13-1
- Formel: C36H63N3O9
- Molecular Weight:681.90
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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ACAT |
Enniatin A exhibits cytotoxic effects in HeLa cell lines with IC50s of 1.15 μM concentration for 24 h and 0.57 μM concentration for 48 h[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2503-13-1
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Molecular Weight 681.90
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Formel C36H63N3O9
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SMILES
CC[C@@H]([C@]1([H])N(C([C@H](OC(C(N(C([C@@H](C(C)C)OC([C@@]([C@@H](C)CC)([H])N(C)C([C@](C(C)C)([H])OC1=O)=O)=O)=O)C)[C@@H](C)CC)=O)C(C)C)=O)C)C
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Structure Classification
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Initial Source
Fusarium sp.
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Tomoda H, et al. Inhibition of acyl-CoA: cholesterol acyltransferase activity by cyclodepsipeptide antibiotics. J Antibiot (Tokyo). 1992 Oct;45(10):1626-32. [Content Brief]
[2]. Mamur S, et al. Assessment of cytotoxic and genotoxic effects of enniatin-A in vitro. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Aug;35(8):1633-1644. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Enniatin A Related Classifications
HY-N6702 Related Classifications
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