Eda - ectodysplasin-A Gene

Predicted to enable death receptor agonist activity and death receptor binding activity. Predicted to be involved in several processes, including cytokine-mediated signaling pathway; positive regulation of NF-kappaB transcription factor activity; and regulation of NIK/NF-kappaB signaling. Predicted to act upstream of or within several processes, including animal organ development; cell-matrix adhesion; and positive regulation of signal transduction. Predicted to be located in apical part of cell; endoplasmic reticulum membrane; and lipid droplet. Predicted to be integral component of plasma membrane. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Orthologous to human EDA (ectodysplasin A). [provided by Alliance of Genome Resources, Apr 2022]