Glutaminase
Based on 1 Customer Validation
Glutaminase is a metabolic enzyme. Glutaminase catalyzes the hydrolysis of glutamine to glutamate. Glutaminase isoenzymes are encoded by Gls and Gls2 genes. Proteins GLS and GLS2 have different kinetic, immunologic, and molecular characteristics. Glutaminase can be used in the research of cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 9001-47-2
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
3.5.1.2
50 - 200 U/mg protein
One unit is defined as the amount of enzyme that will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37°C
Chemical Information
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CAS. Nr. 9001-47-2
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Appearance Solid
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Color Off-white to light yellow
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SMILES
[Glutaminase]
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Synonyms
GLS
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Lösungsmittel & Löslichkeit
H2O : 1 mg/mL (Need ultrasonic and warming)
Reinheit & Dokumentation
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Data Sheet (264 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Wang JB, et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 2010 Sep 14;18(3):207-19. [Content Brief]
[2]. Matés JM, et al. Glutaminase isoenzymes in the metabolic therapy of cancer. Biochim Biophys Acta Rev Cancer. 2018 Dec;1870(2):158-164. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Glutaminase Related Classifications
HY-P2760 Related Classifications
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