HZ52
Based on 1 Customer Validation
HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 98.3%
- CAS. Nr.: 1077626-51-7
- Formel: C24H26ClN3O2S
- Molecular Weight:456.00
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
1.6 μM
Compound: 7a
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Inhibition of PGES1 in human A549 cell microsome assessed as PGE2 formation by cell-free assay
Inhibition of PGES1 in human A549 cell microsome assessed as PGE2 formation by cell-free assay
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[PMID: 19053751] |
| PMNL | IC50 |
0.7 μM
Compound: 7a
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Inhibition of 5-LO in PMNL cells
Inhibition of 5-LO in PMNL cells
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[PMID: 19053751] |
Chemical Information
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CAS. Nr. 1077626-51-7
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Appearance Solid
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Molecular Weight 456.00
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Formel C24H26ClN3O2S
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Color White to off-white
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SMILES
ClC1=CC(NC2=CC=C(C=C2)C3=CC=CC=C3)=NC(SC(C(O)=O)CCCCCC)=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
HZ52 Related Classifications
HY-112553 Related Classifications
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