IMG-2005
IMG-2005 is a TLR signaling pathway inhibitor. IMG-2005 mimics the Toll/interleukin-1 receptor (TIR) domain of MyD88, thereby preventing its homodimerization, which causes damage to tracheal epithelial cells and triggers pulmonary immune diseases.
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- CAS. Nr.: 1229954-79-3
- Formel: C140H227N45O33S
- Molecular Weight:3100.65
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 1229954-79-3
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Molecular Weight 3100.65
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Formel C140H227N45O33S
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Sequence
Asp-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Arg-Asp-Val-Leu-Pro-Gly-Thr
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Sequence Shortening
DRQIKIWFQNRRMKWKKRDVLPGT
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Newkirk MM, et al. Chronic smoke exposure induces rheumatoid factor and anti-heat shock protein 70 autoantibodies in susceptible mice and humans with lung disease. Eur J Immunol. 2012 Apr;42(4):1051-61. [Content Brief]
[2]. Giangreco A, et al. Myd88 deficiency influences murine tracheal epithelial metaplasia and submucosal gland abundance. J Pathol. 2011 Jun;224(2):190-202. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
IMG-2005 Related Classifications
HY-P10718 Related Classifications
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