KRAS-IN-47
KRAS-IN-47 is a KRAS inhibitor with IC50 < 50 nM against KRAS G12V. KRAS-IN-47 can be used for the study of cancers.
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- CAS. Nr.: 3079342-05-2
- Formel: C33H27D2F5N6O2
- Molecular Weight:638.63
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Beschreibung
In Vitro
KRAS-IN-47 (Example 28) is a KRAS inhibitor with IC50 < 50 nM against KRAS G12V[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Parmacokinetics
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 3079342-05-2
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Molecular Weight 638.63
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Formel C33H27D2F5N6O2
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SMILES
FC1=C(C2=CC(N)=CC3=C2C(C#C)=C(F)C(F)=C3)N=CC4=C1N=C(N=C4N5[C@@]6([H])[C@](COCC5)([H])[C@@H]6F)OC([2H])([2H])[C@@]78N(CCC8)C[C@@H](C7)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
KRAS-IN-47 Related Classifications
HY-179253 Related Classifications
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