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Art. -Nr.: HY-N19855

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Merulinic acid

(Synonyms: Geranicardic acid)

Merulinic acid (Geranicardic acid) is an acetylcholinesterase (AChE) inhibitor with an IC₅₀ >94 μM against electric eel-derived AChE. Merulinic acid can be used for the research of alzheimer’s disease.

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CAS. Nr.: 69506-63-4
Formel: C₂₄H₃₈O₃
Molecular Weight:374.56

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Merulinic acid Chemical Structure

CAS. Nr.: 69506-63-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

electric eel AChE

>94 μM (IC₅₀)

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen :

AChE
BChE

In Vitro

Merulinic acid (8-94 μM; 5 min) inhibits the activity of purified AChE from Electrophorus electricus by a maximum of 40%, with an IC₅₀ value >94 μM^[1].
Merulinic acid (20-213 μM; 10 min) induces conformational changes in purified AChE from Electrophorus electricus, decreasing the intrinsic tryptophan fluorescence F/F₀ ratio by approximately 80% at concentrations up to 213 μM, without shifting the fluorescence emission maximum^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 69506-63-4
Molecular Weight 374.56
Formel C₂₄H₃₈O₃
SMILES

CCCCCCCC/C=C\CCCCCCCC1=C(C(O)=CC=C1)C(O)=O
Synonyms

Geranicardic acid
Structure Classification
- Antibiotics
Initial Source
- Microorganisms
Merulius tremellosus
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Stasiuk M, et al. Phenolic lipids affect the activity and conformation of acetylcholinesterase from Electrophorus electricus (Electric eel). Nutrients. 2014;6(5):1823-1831. Published 2014 Apr 30. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
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Merulinic acid

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Merulinic acid Related Classifications

HY-N19855 Related Classifications