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Miptenalimab

(Synonyms: BI-754111)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Miptenalimab (BI-754111) is an anti-human LAG-3 antibody (KD: 88.6 nM for h LAG-3). Miptenalimab blocks the interaction of LAG-3 with its ligand MHC-II.

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  • Reinheit: 97.04%
  • CAS. Nr.: 2249882-55-9
  • Molecular Weight:145.84 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Miptenalimab
  • Experimental Validation Results for Miptenalimab
  • Experimental Validation Results for Miptenalimab
  • Miptenalimab Chemical Structure
    Miptenalimab Chemical Structure
CAS. Nr.: 2249882-55-9
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Miptenalimab. The EC50 for this effect is 673.3 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells labeling Miptenalimab (HY-P99736, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Miptenalimab Chemical Structure
    1/16
  • Miptenalimab
  • Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Miptenalimab. The EC50 for this effect is 673.3 ng/mL.
  • Flow cytometric analysis of 1X106 Jurkat cells labeling Miptenalimab (HY-P99736, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).