Nasunin
Based on 1 publication(s) in Google Scholar
Nasunin, an antioxidant anthocyanin, possesses antiangiogenic activity.
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- Reinheit: 99.34%
- CAS. Nr.: 28463-30-1
- Formel: C42H47ClO23
- Molecular Weight:955.26
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Speicherung:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Nasunin
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Biologische Aktivität
Nasunin at higher 10 µM suppresses microvessel outgrowth in an ex vivo angiogenesis assay using a rat aortic ring[1].
Nasunin suppresses HUVEC proliferation in a dose-dependent manner (50-200 µM)[1].
Nasunin diminishes LPS-induced nuclear factor-κB (NF-κB) activation by suppressing the
degradation of inhibitor of κB-α and nuclear translocation of p65 subunit of NF-κB. Nasunin also attenuates the phosphorylation of Akt and p38, signaling molecules involved in pro-inflammatory mediator production[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 28463-30-1
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Appearance Solid
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Molecular Weight 955.26
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Formel C42H47ClO23
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Color Brown to black
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SMILES
O[C@H]([C@@H]([C@H]([C@@H](O1)C)OC(/C=C/C2=CC=C(C=C2)O)=O)O)[C@@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC4=CC(C(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)=CC(O)=C6)=C6[O+]=C4C7=CC(O)=C(C(O)=C7)O.[Cl-]
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Synonyms
Delphinidin-3-(p-coumaroylrutinoside)-5-glucoside
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Biochim Biophys Acta Mol Basis Dis
Neutrophil-derived thrombospondin-1 (THBS1) drives type 2 diabetes-induced osteoporosis via CD36-PPARγ-POU2F2 signaling. [Abstract]2025 Dec 15;1872(3):168139. PMID: 41407214
Reinheit & Dokumentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Kiminori Matsubara, et al. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels. J Agric Food Chem. 2005 Aug 10;53(16):6272-5. [Content Brief]
[2]. Wataru Komatsu, et al. Nasunin inhibits the lipopolysaccharide-induced pro-inflammatory mediator production in RAW264 mouse macrophages by suppressing ROS-mediated activation of PI3 K/Akt/NF-κB and p38 signaling pathways. Biosci Biotechnol Biochem. 2017 O [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Nasunin Related Classifications
HY-N9396 Related Classifications
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