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Art. -Nr.: HY-W743952

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Nicergoline-d₃

Nicergoline-d₃ is the deuterium labeled Nicergoline (HY-B0702). Nicergoline, an ergoline derivative ester of bromonicotinic acid, is a potent, selective and orally active antagonist of α1A-adrenoceptor. Nicergoline has vasodilator effects. Nicergoline also has ameliorative effects on cognitive function in mouse models of Alzheimer's disease.

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Formel: C₂₄H₂₃D₃BrN₃O₃
Molecular Weight:487.40

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (240 KB)

Nicergoline-d₃ Chemical Structure

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Biologische Aktivität

Beschreibung

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In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled Cas 27848-84-6
Molecular Weight 487.40
Formel C₂₄H₂₃D₃BrN₃O₃
SMILES

[H][C@@]1(CC2=CN(C3=C2C4=CC=C3)C([2H])([2H])[2H])[C@@]4(C[C@H](CN1C)COC(C5=CC(Br)=CN=C5)=O)OC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.