Niruriside
Niruriside is a HIV REV/RRE complex inhibitor. Niruriside specifically inhibits the binding interaction between HIV REV protein and RRE RNA, with an IC50 of 3.3 μM, and shows no significant activity against the unrelated R17 capsid protein/operator RNA binding system. At the tested concentrations, Niruriside fails to protect CEM-SS cells from acute HIV-1 infection. Niruriside can be used in the research of human immunodeficiency virus (HIV) infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 173268-90-1
- Formel: C38H42O17
- Molecular Weight:770.73
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Niruriside (260 μM; 6 days post-infection, plus 4 h XTT incubation) does not protect CEM-SS cells from acute HIV-1 RF infection at concentrations up to 260 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CEM-SS cells infected with HIV-1 RF
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Concentration:260 μM
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Incubation Time:6 days post-infection, plus 4 h XTT incubation
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Result:Did not protect CEM-SS cells from acute HIV-1 infection at concentrations.
Chemical Information
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CAS. Nr. 173268-90-1
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Molecular Weight 770.73
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Formel C38H42O17
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SMILES
O=C(O[C@@H]1[C@@H](O)[C@H](COC(/C=C/C2=CC=CC=C2)=O)O[C@@]1(O[C@@H]3[C@H](OC(C)=O)[C@@H](O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3)COC(C)=O)/C=C/C4=CC=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Niruriside Related Classifications
HY-165513 Related Classifications
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