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Art. -Nr.: HY-105165

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Nortopixantrone

Name: Nortopixantrone
Brand: MedChemExpress
SKU: HY-105165
Availability: PreOrder

(Synonyms: BBR 3438 free base)

Nortopixantrone (BBR 3438 free base) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone plays an important role in cacner research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 156090-17-4
Formel: C₂₀H₂₄N₆O₂
Molecular Weight:380.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Nortopixantrone Chemical Structure

CAS. Nr.: 156090-17-4

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Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Nortopixantrone (BBR 3438 free base) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone plays an important role in cacner research^[1].

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
LoVo	IC₅₀	>100 μg/mL Compound: 13z	In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line. In vitro cytotoxicity on human colon adenocarcinoma resistant to doxorubicin (LoVo/Dx ) tumor cell line.	[PMID: 9876113]
LoVo	IC₅₀	0.54 μg/mL Compound: 13z	In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line. In vitro cytotoxicity on human colon adenocarcinoma (LoVo ) tumor cell line.	[PMID: 9876113]

Chemical Information

CAS. Nr. 156090-17-4
Molecular Weight 380.44
Formel C₂₀H₂₄N₆O₂
SMILES

O=C1C2=C(C3=NN(CCNCCO)C4=CC=C(C1=C34)NCCNC)C=NC=C2
Synonyms

BBR 3438 free base
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. R-D Hofheinz, et al. BBR 3438, a novel 9-aza-anthrapyrazole, in patients with advanced gastric cancer: a phase II study group trial of the Central European Society of Anticancer-Drug Research (CESAR). Clinical Trial Invest New Drugs. 2005 Aug;23(4):363-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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