Oxybenzone-13C6
Oxybenzone-13C6 (Benzophenone 3-13C6) is the 13C-labeled Oxybenzone (HY-A0067). Oxybenzone (Benzophenone 3) is a commonly used UV filter in sun tans and skin protectants. Oxybenzone act as endocrine disrupting chemicals (EDCs) and can pass through the placental and blood-brain barriers. Benzophenone-3 impairs autophagy, alters epigenetic status, and disrupts retinoid X receptor signaling in apoptotic neuronal cells.
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- Formel: C813C6H12O3
- Molecular Weight:234.20
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 131-57-7
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Appearance Solid
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Molecular Weight 234.20
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Formel C813C6H12O3
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Color White to off-white
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SMILES
O=C(C1=CC=C(OC)C=C1O)[13C]2=[13CH][13CH]=[13CH][13CH]=[13CH]2
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Synonyms
Benzophenone 3-13C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (764 KB)
- English - EN (764 KB)
- Français - FR (764 KB)
- Deutsch - DE (764 KB)
- Norwegian - NO (764 KB)
- Español - ES (764 KB)
- Swedish - SV (764 KB)
- Italian - IT (764 KB)
- Korean - KR (764 KB)
- Portuguese - PT (764 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Wnuk A, et al. Prenatal exposure to benzophenone-3 (BP-3) induces apoptosis, disrupts estrogen receptor expression and alters the epigenetic status of mouse neurons. J Steroid Biochem Mol Biol. 2018;182:106-118. [Content Brief]
[2]. DiNardo JC, et al. Can oxybenzone cause Hirschsprung's disease?. Reprod Toxicol. 2019;86:98-100. [Content Brief]
[3]. Wnuk A, et al. Benzophenone-3 Impairs Autophagy, Alters Epigenetic Status, and Disrupts Retinoid X Receptor Signaling in Apoptotic Neuronal Cells. Mol Neurobiol. 2018;55(6):5059-5074. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Oxybenzone-13C6 Related Classifications
HY-A0067S1 Related Classifications
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