VEGF-D
VEGF-D, encoded by FIGF and originally described as a fos-induced gene product, is a proteolytically matured ligand for VEGFR2 and VEGFR3 with actions largely parallel to VEGF-C. Full-length VEGF-D must be cleaved to release the mature dimer for efficient receptor activation. It contributes to lymphatic vessel development and is highly expressed in lung, where it participates in alveolar and surfactant homeostasis. Serum VEGF-D is an established diagnostic biomarker for lymphangioleiomyomatosis, and tumor-expressed VEGF-D promotes lymphatic metastasis. Recombinant VEGF-D is used in lymphangiogenesis assays, VEGFR3-binding studies, and biomarker assay development for LAM and cancer.
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VEGF-D Recombinant Proteins (8)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
