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United States

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Art. -Nr.: HY-183782

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SA1103064

SA1103064 is a potent antibiotic with antibacterial activity against multiple resistant bacterial strains. SA1103064 binds to the bacterial ribosome's nascent peptide exit tunnel. SA1103064 can be used for the research of bacterial infections.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Formel: C₃₉H₅₀FN₇O₆
Molecular Weight:731.86

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

SA1103064 Chemical Structure

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Preis

Verfügbarkeit

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Antibiotic Isoform-spezifische Produkte anzeigen :

In Vitro

SA1103064 (compound 48a) binds to the E. coli ribosome's nascent peptide exit tunnel, forming π-stacking interactions with U1782-U2586 and van der Waals interactions with U2585, occupying the site of tetracenomycin X and mimicking VS1 binding contacts^[1].
SA1103064 exhibits potent antibacterial activity against multiple Gram-positive strains, including drug-resistant isolates, with MIC values ranging from 1 to 8 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

Molecular Weight 731.86
Formel C₃₉H₅₀FN₇O₆
SMILES

[H][C@]12CCCN1C(C3=COC(C[C@@H](C[C@@H](/C=C(/C=C/CNC(/C=C/[C@H]([C@H](OC2=O)C(C)C)CCCCCN4C=C(N=N4)C5=CC=NC=C5)=O)C)O)F)=N3)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Lee IJ, et al. Structure-based design and synthesis of group A streptogramins that bind to the nascent peptide exit tunnel of the ribosome. Eur J Med Chem. 2026 May 9;316:118947. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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