SB-414796
SB-414796 is a selective, orally active and cross the blood-brain barrier dopamine D3 receptor antagonist with Ki values of 4, 400 nM for D3, D2, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 264262-71-7
- Formel: C29H36N4O4S
- Molecular Weight:536.69
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
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D3 Receptor 4 nM (Ki) |
D2 Receptor 400 nM (Ki) |
Chemical Information
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CAS. Nr. 264262-71-7
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Molecular Weight 536.69
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Formel C29H36N4O4S
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SMILES
CS(C1=CC2=C(C=C1)CCN(CC2)CC[C@H]3CC[C@@H](CC3)NC(C4=CC=CC(C5=NOC(C)=N5)=C4)=O)(=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Macdonald GJ, et al. Design and synthesis of trans-3-(2-(4-((3-(3-(5-methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro-1H-3-benzazepine (SB-414796): a potent and selective dopamine D3 receptor antagonist. J Med Chem. 2003 Nov 6;46(23):4952-64. [Content Brief]
[2]. Heidbreder CA, et al. Current perspectives on selective dopamine D(3) receptor antagonists as pharmacotherapeutics for addictions and related disorders. Ann N Y Acad Sci. 2010 Feb;1187:4-34. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SB-414796 Related Classifications
HY-123473 Related Classifications
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