SC-50605
SC-50605 and SC-51146 are second-generation leukotriene B4 (LTB4) receptor antagonists that effectively inhibit LTB4-induced chemotaxis in guinea pigs. SC-50605 targets the LTB4 receptor and has the potential to inhibit inflammatory diseases such as asthma, rheumatoid arthritis, and skin diseases..
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- CAS. Nr.: 138828-39-4
- Formel: C30H35NO6S
- Molecular Weight:537.67
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
LTB4[1]
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HL-60 | IC50 |
660 nM
Compound: 35
|
Inhibitory activity against LTB4 production in HL60s.
Inhibitory activity against LTB4 production in HL60s.
|
[PMID: 7699700] |
| HL-60 | IC50 |
928 nM
Compound: 35
|
Inhibitory activity against PGE-2 production in HL60s.
Inhibitory activity against PGE-2 production in HL60s.
|
[PMID: 7699700] |
Chemical Information
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CAS. Nr. 138828-39-4
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Molecular Weight 537.67
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Formel C30H35NO6S
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SMILES
O=C(O)C1CCC2=CC=C(C(CCC)=C2O1)OCCCOC3=CC=C(C(OC)=C3CC4CC4)C5=CSC=N5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)