SLR080811
SLR080811 is a guanidine-based selective sphingosine kinase 2 (SphK2) inhibitor with a Ki of 1.3 μM, exhibiting ~10-fold selectivity over SphK1 (Ki = 12 μM). SLR080811 reduces sphingosine 1-phosphate (S1P) levels in vitro, but drives a SphK1-dependent increase in S1P in mice. SLR080811 can be used for cancers and fibrosis research.
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- CAS. Nr.: 1449765-65-4
- Formel: C21H31N5O
- Molecular Weight:369.50
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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SphK2 1.3 μM (Ki) |
SphK1 12 μM (Ki) |
Chemical Information
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CAS. Nr. 1449765-65-4
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Molecular Weight 369.50
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Formel C21H31N5O
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SMILES
N=C(N1[C@@H](C2=NC(C3=CC=C(C=C3)CCCCCCCC)=NO2)CCC1)N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SLR080811 Related Classifications
HY-12896 Related Classifications
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