SNAP 398299
SNAP 398299 is a Gal3 receptor antagonist with potential anxiolytic and antidepressant effects. SNAP 398299 can partially reverse the neuropeptide Galanin-induced inhibition of dorsal raphe cell firing and the Galanin-induced hyperpolarizing current.
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- CAS. Nr.: 903878-06-8
- Formel: C27H24F3N3O2
- Molecular Weight:479.49
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
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Biologische Aktivität
Chemical Information
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CAS. Nr. 903878-06-8
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Molecular Weight 479.49
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Formel C27H24F3N3O2
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SMILES
O=C1/C(C2=CC=CC=C2N1C3=CC(OCCN4CCCC4)=CC=C3)=N/C5=CC=CC(C(F)(F)F)=C5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Swanson CJ, et al. Anxiolytic- and antidepressant-like profiles of the galanin-3 receptor (Gal3) antagonists SNAP 37889 and SNAP 398299. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17489-94. [Content Brief]
[2]. Insights of structure-based pharmacophore studies and inhibitor design against Gal3 receptor through molecular dynamics simulations [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SNAP 398299 Related Classifications
HY-123708 Related Classifications
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