TY-011
TY-011 is an Aurora A/B kinase inhibitor. TY-011 induces abnormal microtubule-kinetochore attachment, leading to DNA damage and apoptosis (Apoptosis) in human gastric cancer cells, and ultimately inhibits cancer cell proliferation, with an IC50 value ranging from 0.11 to 4.49 μM in human gastric cancer cell lines. TY-011 has potential applications in gastric cancer research.
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- CAS. Nr.: 1389439-77-3
- Formel: C18H16ClN5
- Molecular Weight:337.81
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
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Aurora A |
Aurora B |
Chemical Information
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CAS. Nr. 1389439-77-3
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Molecular Weight 337.81
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Formel C18H16ClN5
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SMILES
CC1=C(C(N2)=NN1)N=C(C3=CC=CC=C3Cl)C4=C2C=C(CC)N=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)