UK 357903
UK 357903 is a selective inhibitor for phosphodiesterase 5 (PDE5), with IC50s of 1.7 and 714 nM, for PDE5 and PDE6. UK 357903 exhibits vasodilatory effects on the mesenteric and hindlimb vascular beds, and is potential for ameliorating erectile dysfunction.
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- CAS. Nr.: 247580-98-9
- Formel: C27H34N8O5S
- Molecular Weight:582.67
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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PDE5 1.7 nM (IC50) |
PDE6 714 nM (IC50) |
Chemical Information
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CAS. Nr. 247580-98-9
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Molecular Weight 582.67
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Formel C27H34N8O5S
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SMILES
O=C1N=C(C2=C(OCCOC)N=CC(S(=O)(N3CCN(CC3)CC)=O)=C2)NC4=C(CC)N(CC5=NC=CC=C5)N=C41
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)