Viscumneoside V
Viscumneoside V is a plant-derived anti-inflammatory agent present in Viscum album var. coloratum. Viscumneoside V inhibits the expression of MCP-1 and promotes the production of RANTES in LPS-stimulated immune cells. Viscumneoside V can be used for research related to skin rashes.
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- Reinheit: 98.24%
- CAS. Nr.: 119016-92-1
- Formel: C32H40O19
- Molecular Weight:728.65
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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CCR2 |
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Cell Line
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Type | Value | Description | References |
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| BMDC | IC50 |
50 μM
Compound: 12
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Antiinflammatory activity in C57BL/6 mouse BMDCs assessed as inhibition of LPS-stimulated IL-12p40 production treated 1 hr before LPS challenge measured 18 hrs post stimulation by ELISA
Antiinflammatory activity in C57BL/6 mouse BMDCs assessed as inhibition of LPS-stimulated IL-12p40 production treated 1 hr before LPS challenge measured 18 hrs post stimulation by ELISA
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[PMID: 23484668] |
Viscumneoside V (1-50 μM; 25 h) potently inhibits MCP-1 production and promotes RANTES production in LPS-stimulated RAW264.7 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:LPS-stimulated RAW264.7 murine macrophage cells
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Concentration:1-50 μM
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Incubation Time:1 h (pre-incubation); 24 h (LPS stimulation)
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Result:Significantly suppressed LPS-induced MCP-1 production at all tested concentrations.
Showed dose-dependent reductions.\nSignificantly increased LPS-induced RANTES production at 25, 50 μM.
Showed smaller increases at 1, 5, 10 μM.
Chemical Information
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CAS. Nr. 119016-92-1
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Appearance Solid
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Molecular Weight 728.65
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Formel C32H40O19
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Color Off-white to light yellow
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SMILES
O=C1C2=C(O)C=C(O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O[C@H]4[C@@H]([C@](O)(CO4)CO[C@H]5[C@@H]([C@](O)(CO5)CO)O)O)C=C2O[C@H](C6=CC(OC)=C(C=C6)O)C1
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Viscumneoside V Related Classifications
HY-N17908 Related Classifications
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