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Zifibancimig

(Synonyms: RO-7250284)
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Based on 1 Customer Validation

Zifibancimig (RO-7250284) is a monoclonal antibody against VEGF-A and Ang-2, with affinities of 4 pM and 2 pM, respectively. Zifibancimig has high stability, maintains target-binding capability under physiological stress and storage conditions, and is designed for sustained long-term ocular delivery via the Port Delivery implant device. Zifibancimig can be used in the research of retinal diseases.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 99.00%
  • CAS. Nr.: 2517939-46-5
  • Molecular Weight:47.921 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Zifibancimig
  • Experimental Validation Results for Zifibancimig
  • Experimental Validation Results for Zifibancimig
  • Experimental Validation Results for Zifibancimig
  • Zifibancimig Chemical Structure
    Zifibancimig Chemical Structure
CAS. Nr.: 2517939-46-5
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Zifibancimig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Fab-G1-kappa

  • 1/16

    Loaded Zifibancimig on FAB2G biosensor, can bind VEGF121 Protein, Human (120 a.a, HY-P7420) with an affinity constant of <1.000E-11 M as determined in BLI assay.

  • 1/16

    Loaded Zifibancimig on FAB2G biosensor, can bind Angiopoietin-2 Protein, Human (222a.a, HEK293, His, HY-P7510) with an affinity constant of 2.091E-09 M as determined in BLI assay.

  • 1/16

    Flow cytometric analysis of 1X106 HeLa cells with Zifibancimig (HY-P990689, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Zifibancimig Chemical Structure
    1/16
  • Zifibancimig
  • Loaded Zifibancimig on FAB2G biosensor, can bind VEGF121 Protein, Human (120 a.a, HY-P7420) with an affinity constant of <1.000E-11 M as determined in BLI assay.
  • Loaded Zifibancimig on FAB2G biosensor, can bind Angiopoietin-2 Protein, Human (222a.a, HEK293, His, HY-P7510) with an affinity constant of 2.091E-09 M as determined in BLI assay.
  • Flow cytometric analysis of 1X106 HeLa cells with Zifibancimig (HY-P990689, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. AF 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Fab-G1-kappa