AZ12441970
AZ12441970 is a potent and selectiveToll-like receptor 7 (TLR7) agonist, exhibiting pEC50s of 6.8 and 6.6 for human and rat TLR7. AZ12441970 shows efficacy in a mouse allergic airway model with minimal induction of systemic IFN-α. AZ12441970 can be used for allergic airway disease research.
For research use only. We do not sell to patients.
- CAS No.: 929551-91-7
- Formula: C27H41N7O4
- Molecular Weight:527.66
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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human TLR7 6.8 (pEC50) |
Rat TLR7 6.6 (pEC50) |
Chemical Information
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CAS No. 929551-91-7
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Molecular Weight 527.66
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Formula C27H41N7O4
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SMILES
O=C(OC)CC1=CC=CC(CN(CCCN2C(NC3=C(N)N=C(OCCCC)N=C23)=O)CCCN(C)C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AZ12441970 Related Classifications
HY-117686 Related Classifications
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