VU0455691
VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1).
For research use only. We do not sell to patients.
- CAS No.: 1392443-41-2
- Formula: C24H25N5O3S
- Molecular Weight:463.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
0.23 μM
Compound: 12a, VU0455691
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Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fluorescence analysis
Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fluorescence analysis
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[PMID: 22749871] |
Chemical Information
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CAS No. 1392443-41-2
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Molecular Weight 463.55
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Formula C24H25N5O3S
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SMILES
O=C(C1CN(C1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O)N4CC5CN(CC5C4)C6=CC=NC=C6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
VU0455691 Related Classifications
HY-116569 Related Classifications
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