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Cat. No.: HY-136622

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A-420983

A-420983 is a potent, orally active inhibitor of Lck and can be used in studies involving animal models of delayed-type hypersensitivity and organ transplant rejection.

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CAS No.: 330789-03-2
Formule: C₃₃H₃₉N₉O₂
Masse moléculaire:593.72

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

A-420983 Chemical Structure

CAS No.: 330789-03-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

A-420983 is a potent, orally active inhibitor of Lck and can be used in studies involving animal models of delayed-type hypersensitivity and organ transplant rejection^[1].

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Chemical Information

CAS No. 330789-03-2
Masse moléculaire 593.72
Formule C₃₃H₃₉N₉O₂
SMILES

O=C(C(N1C)=CC2=C1C=CC=C2)NC3=CC=C(C4=NN([C@H]5CC[C@H](N6CCN(C)CC6)CC5)C7=NC=NC(N)=C74)C=C3OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Borhani DW, et al. A-420983: a potent, orally active inhibitor of lck with efficacy in a model of transplant rejection. Bioorg Med Chem Lett. 2004;14(10):2613-2616. [Content Brief]

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Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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A-420983

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