BDM88855
BDM88855 is an allosteric inhibitor for the homolog AcrB protein. BDM88855 can boost the antibacterial effect of a panel of antibiotics (eg: Oxacillin (HY-B0925A), Linezolid (HY-10394), Novobiocin (HY-B0425), etc.) on wild-type E. coli.
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- CAS No.: 2892824-25-6
- Formule: C13H14ClN3
- Masse moléculaire:247.72
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
Chemical Information
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CAS No. 2892824-25-6
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Masse moléculaire 247.72
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Formule C13H14ClN3
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SMILES
ClC1=C(N2CCNCC2)N=C(C=CC=C3)C3=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Plé C, et al. Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps. Nat Commun. 2022 Jan 10;13(1):115. [Content Brief]
[2]. Bera A, et al. Exploring transmembrane allostery in the MexB: DB08385 variant as a promising inhibitor-like candidate against Pseudomonas aeruginosa antibiotic resistance: a computational study. Phys [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)