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Cat. No.: HY-P992331

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CEL383

CEL383 is a human monoclonal antibody targeting TREM1. CEL383 blocks the TREM1 signaling pathway, thereby alleviating inflammation and reducing the levels of inflammatory mediators. CEL383 can be used in research related to inflammatory bowel disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CEL383 Chemical Structure

Size

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Species Reactivity

Human

IC₅₀ & Target^[1]^[2]

TREM-1

Voir tous les produits spécifiques à Isoform TREM receptor :

In Vitro

CEL383 inhibits TREM1 signaling in preclinical assays, reducing levels of clinically relevant inflammatory mediators linked to inflammatory conditions^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gene ID

54210 [NCBI]

Accession

Q9NP99

Target

TREM-1/CD354

Conjugated

Unconjugated

Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.

Format

Product Image

Application

ELISA, FACS, Functional assay

Chemical Information

Formulation

Please refer to the lot-specific COA for specific buffer information.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Inhibitory Antibodies User Guide (603 KB)

Références

[1]. Diress M, Mooranian A, Al‑Salami H. Industry updates in the field of therapeutic delivery in June 2024. Therapeutic Delivery. 2024;15(11):819‑828.

[2]. AbbVie. AbbVie acquires Celsius Therapeutics [press release]. North Chicago (IL): AbbVie News Center; 2024 Jun 27.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- Species Reactivity
- IC₅₀ & Target
- In Vitro
- Gene ID
- Accession
- Target
- Conjugated
- Reconsititution
- Format
- Application
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

CEL383

DPBS Buffer (1×)

PBS Buffer (1×)

Cytotoxicity LDH Assay Kit

Voir tous les produits spécifiques à Isoform TREM receptor