Clausarin
Clausarin is a selective inhibitor of P-glycoprotein (P-gp), inhibiting P-gp-mediated drug efflux. Clausarin significantly inhibits Daunorubicin (HY-13062A) efflux in K562/R7 human leukemia cells overexpressing P-gp (with Cyclosporin A (HY-B0579) as a positive control). Clausarin can be naturally extracted from the roots of Citrus sinensis (sweet orange) and can be used in research related to overcoming multidrug resistance (MDR) in tumors.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 62770-67-6
- Formule: C24H28O4
- Masse moléculaire:380.48
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | EC50 |
2.98 μg/mL
Compound: 3
|
Cytotoxicity against human A549 cells after 3 days by sulforhodamine B assay
Cytotoxicity against human A549 cells after 3 days by sulforhodamine B assay
|
[PMID: 19635670] |
Chemical Information
-
CAS No. 62770-67-6
-
Masse moléculaire 380.48
-
Formule C24H28O4
-
SMILES
O=C1OC2=C(C(C)(C)C=C)C3=C(C=CC(C)(C)O3)C(O)=C2C=C1C(C)(C)C=C
-
Structure Classification
-
Initial Source
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Clausarin Related Classifications
HY-N16684 Related Classifications
Powered by Bioz