Co 101244
Co-101244 (PD 174494) is an NMDA receptor blocker that specifically targets the NR2B subunit.
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- CAS No.: 193359-26-1
- Formule: C21H27NO3
- Masse moléculaire:341.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Oocyte | IC50 |
>100 μM
Compound: 10e
|
In vitro inhibitory concentration against NMDA responses at cloned NR1A/2A receptors expressed in Xenopus oocytes
In vitro inhibitory concentration against NMDA responses at cloned NR1A/2A receptors expressed in Xenopus oocytes
|
[PMID: 10425109] |
| Oocyte | IC50 |
>100 μM
Compound: 10e
|
In vitro inhibitory concentration against NMDA responses at NR1A/2C receptors expressed in Xenopus oocytes
In vitro inhibitory concentration against NMDA responses at NR1A/2C receptors expressed in Xenopus oocytes
|
[PMID: 10425109] |
| Oocyte | IC50 |
0.043 μM
Compound: 10e
|
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes
In vitro inhibitory concentration against NMDA responses at NR1A/2B receptors expressed in Xenopus oocytes
|
[PMID: 10425109] |
Chemical Information
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CAS No. 193359-26-1
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Masse moléculaire 341.44
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Formule C21H27NO3
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SMILES
OC1=CC=C(C=C1)OCCN2CCC(CC3=CC=C(C)C=C3)(CC2)O
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Synonyms
PD 174494
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)