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Cat. No.: HY-153902

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DG-8

DG-8 is a potent inhibitor of STAT3-dependent transcription (IC₅₀ 0.98 μM). DG-8 is a fluorescent probe that contains a fluorescent dansyl moiety.

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Formule: C₂₇H₂₈Cl₃N₅O₄S
Masse moléculaire:624.97

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DG-8 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

DG-8 is a potent inhibitor of STAT3-dependent transcription (IC₅₀ 0.98 μM). DG-8 is a fluorescent probe that contains a fluorescent dansyl moiety^[1].

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Chemical Information

Masse moléculaire 624.97
Formule C₂₇H₂₈Cl₃N₅O₄S
SMILES

O=C(N(CCN(C)S(C1=C(C=CC=C2N(C)C)C2=CC=C1)(=O)=O)C)C3=CC=C(N4C(C(Cl)=C(Cl)C=N4)=O)C=C3.Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Busker S, et al. Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death. Sci Adv. 2020 Mar 20;6(12):eaax7945. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

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DG-8

Voir tous les produits spécifiques à Isoform STAT

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

DG-8 Related Classifications

HY-153902 Related Classifications