ETP-45835
ETP-45835 is slective and potent MNK inhibitor with IC50s of 575 nM and 646 nM for MNK1 and MNK2, respectively. ETP-45835 shows little activity against 24 other kinases. ETP-45835 inhibits eIF4E Ser209 phosphorylation in cells, and has anticancer effects.
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- CAS No.: 794510-70-6
- Formule: C13H16N4
- Masse moléculaire:228.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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MNK1 575 nM (IC50) |
MNK2 646 nM (IC50) |
Chemical Information
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CAS No. 794510-70-6
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Masse moléculaire 228.29
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Formule C13H16N4
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SMILES
N=1C=CC(=CC1)C2=NNC(=C2)C3CCNCC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ETP-45835 Related Classifications
HY-W846144 Related Classifications
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