Gamhepathiopine
Gamhepathiopine is a thienopyrimidinone compound. Gamhepathiopine exerts antimalarial effects by targeting the Qo site of Plasmodium falciparum cytochrome b and inhibiting the activity of complex III in the electron transport chain.
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- CAS No.: 1620442-30-9
- Formule: C17H19N3OS
- Masse moléculaire:313.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | CC50 |
27.5 μM
Compound: 1
|
Cytotoxicity against CHO cells assessed as cell viability after 24 hrs by MTT assay
Cytotoxicity against CHO cells assessed as cell viability after 24 hrs by MTT assay
|
[PMID: 25791675] |
| Hepatocyte | CC50 |
>200 μM
Compound: 1
|
Cytotoxicity against cynomolgus monkey Primary hepatocyte assessed as cell viability
Cytotoxicity against cynomolgus monkey Primary hepatocyte assessed as cell viability
|
[PMID: 36680984] |
| HepG2 | CC50 |
25.6 μM
Compound: 1
|
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay
|
[PMID: 25791675] |
Chemical Information
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CAS No. 1620442-30-9
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Masse moléculaire 313.42
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Formule C17H19N3OS
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SMILES
CC1=CC=C(C2=CC(N=C(NC(C)(C)C)NC3=O)=C3S2)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)