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Cat. No.: HY-N11638

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Ganoderic acid R

Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1).

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CAS No.: 103963-39-9
Formule: C₃₄H₅₀O₆
Masse moléculaire:554.76

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Ganoderic acid R Chemical Structure

CAS No.: 103963-39-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Vero	IC₅₀	32 μM Compound: 41	Cytotoxicity against African green monkey Vero cells by GFP based microplate assay Cytotoxicity against African green monkey Vero cells by GFP based microplate assay	[PMID: 28504879]

In Vitro

Ganoderic acid R (0-50 µg/mL, 48 h) inhibit the growth by inducing apoptosis on tumor cell lines at the concentrations that more than 20 µg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[1]

Cell Line:

KB-A-1/Dox cells
Concentration:

0, 25, 50 μg/mL
Incubation Time:

48 h
Result:

Induced the cellular apoptosis, the number of apoptotic cells was increased from 35% to 90% during 48 h.

Chemical Information

CAS No. 103963-39-9
Masse moléculaire 554.76
Formule C₃₄H₅₀O₆
SMILES

C[C@@]12C3=CC[C@](C)([C@@](CC4)([H])[C@H](C)[C@@H](OC(C)=O)C/C=C(C)/C(O)=O)[C@]4(C)C3=CC[C@@]1([H])C(C)([C@@H](CC2)OC(C)=O)C
Structure Classification
- Terpenoids
- Triterpenes
Initial Source
- Microorganisms
glossy ganoderma
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ouyang J J, et al. Ganoderic Acid Restores the Sensitivity of Multidrug Resistance Cancer Cells to Doxorubicin. Advanced Materials Research, 2014, 834-836:573-576.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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