Copy Link Print Information

IBI-363

Avis client

Based on 1 Customer Validation

IBI-363 is a PD-1/IL-2 bispecific antibody with functions of blocking the PD-1/PD-L1 pathway and activating the IL-2 pathway. The IL-2 arm of IBI-363 retains affinity for IL-2Rα but attenuates binding ability to IL-2Rβ and IL-2Rγ to reduce toxicity. The PD-1 binding arm of IBI-363 enables PD-1 blockade and selective delivery of IL-2. IBI-363 can be used in cancer research, such as non-small cell lung cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

  • Pureté: 99.92%
  • Masse moléculaire:112.48 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for IBI-363
  • Experimental Validation Results for IBI-363
  • IBI-363 Chemical Structure
    IBI-363 Chemical Structure
Size
Prix
Stock
Quantité
Amount: USD 0.00
Please select quantity
or
or

* Veuillez sélectionner la quantité avant d'ajouter des articles.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
IBI-363 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
  • Activité biologique
  • Chemical Information
  • Pureté et documentation
  • Références
  • Help & FAQs
Top Publications Citing

Use of MCE Products

Voir tous les produits spécifiques à Isoform Interleukin Related

More
Keywords
MOQ
Minimum order quantity
100 mg

Obtenir un devis En stock

Other size
Obtenir un devis
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Enregistrer
Sign in to MedChemExpress
Enregistrer un nouveau compte

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    PD-1/IL-2 α-bias bispecific antibody

  • 1/16

    Immobilized PD-1 Protein, Human (HEK293, HY-P7396) can bind IBI-363. The ED50 for this effect is 4.714 ng/mL.

  • IBI-363 Chemical Structure
    1/16
  • IBI-363
  • Immobilized PD-1 Protein, Human (HEK293, HY-P7396) can bind IBI-363. The ED50 for this effect is 4.714 ng/mL.
  • PD-1/IL-2 α-bias bispecific antibody