Indolidan
Indolidan (LY195115) is an orally active cardiotonic agent and a selective cyclic nucleotide phosphodiesterase inhibitor. Indolidan has a Ki of 80 nM for sarcoplasmic reticulum phosphodiesterase (SR-PDE). Indolidan exhibits positive inotropic and vasodilator effects. Indolidan can be used in the research of diseases such as congestive heart failure.
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- CAS No.: 100643-96-7
- Formule: C14H15N3O2
- Masse moléculaire:257.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 100643-96-7
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Masse moléculaire 257.29
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Formule C14H15N3O2
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SMILES
CC1(C2=CC(C(CC3)=NNC3=O)=CC=C2NC1=O)C
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Synonyms
LY195115
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Hayes JS, et al. Pharmacology of LY195115, a potent, orally active cardiotonic with a long duration of action. J Cardiovasc Pharmacol. 1987 Apr;9(4):425-34. [Content Brief]
[2]. Kauffman RF, et al. LY195115: a potent, selective inhibitor of cyclic nucleotide phosphodiesterase located in the sarcoplasmic reticulum. Mol Pharmacol. 1986 Dec;30(6):609-16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Indolidan Related Classifications
HY-165439 Related Classifications
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