Niruriside
Niruriside is a HIV REV/RRE complex inhibitor. Niruriside specifically inhibits the binding interaction between HIV REV protein and RRE RNA, with an IC50 of 3.3 μM, and shows no significant activity against the unrelated R17 capsid protein/operator RNA binding system. At the tested concentrations, Niruriside fails to protect CEM-SS cells from acute HIV-1 infection. Niruriside can be used in the research of human immunodeficiency virus (HIV) infection.
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- CAS No.: 173268-90-1
- Formule: C38H42O17
- Masse moléculaire:770.73
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Niruriside (260 μM; 6 days post-infection, plus 4 h XTT incubation) does not protect CEM-SS cells from acute HIV-1 RF infection at concentrations up to 260 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CEM-SS cells infected with HIV-1 RF
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Concentration:260 μM
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Incubation Time:6 days post-infection, plus 4 h XTT incubation
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Result:Did not protect CEM-SS cells from acute HIV-1 infection at concentrations.
Chemical Information
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CAS No. 173268-90-1
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Masse moléculaire 770.73
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Formule C38H42O17
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SMILES
O=C(O[C@@H]1[C@@H](O)[C@H](COC(/C=C/C2=CC=CC=C2)=O)O[C@@]1(O[C@@H]3[C@H](OC(C)=O)[C@@H](O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3)COC(C)=O)/C=C/C4=CC=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Niruriside Related Classifications
HY-165513 Related Classifications
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