NU9056 (Standard)
NU9056 (Standard) is the analytical standard of NU9056 (HY-110127). This product is intended for research and analytical applications. NU9056 is a potent and selective Tip60 (KAT5) histone acetyltransferase inhibitor with an of 2 μM. NU9056 shows >16-fold selectivity for Tip60 over PCAF, p300 and GCN5. NU9056 induces apoptosis of prostate cancer cells.
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- CAS No.: 1450644-28-6
- Formule: C6H4N2S4
- Masse moléculaire:232.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1450644-28-6
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Masse moléculaire 232.37
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Formule C6H4N2S4
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SMILES
C1(SSC2=CC=NS2)=CC=NS1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kelly Coffey, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS One. 2012;7(10):e45539. [Content Brief]
[2]. Klotilda Narkaj, et al. Blocking H2A.Z Incorporation via Tip60 Inhibition Promotes Systems Consolidation of Fear Memory in Mice. eNeuro. 2018 Nov 8;5(5):ENEURO.0378-18.2018. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)