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Cat. No.: HY-124731

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PD-321852

PD-321852 is a Chk1 inhibitor, with IC₅₀ of 5 nM. PD-321852 can be used in anti-cancer research.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 622856-21-7
Formule: C₂₄H₁₉Cl₂N₃O₃
Masse moléculaire:468.33

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

PD-321852 Chemical Structure

CAS No.: 622856-21-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

PD-321852 is a Chk1 inhibitor, with IC₅₀ of 5 nM. PD-321852 can be used in anti-cancer research^[1].

IC₅₀ & Target

Chk1

5 nM (IC₅₀)

Voir tous les produits spécifiques à Isoform Checkpoint Kinase (Chk) :

Chemical Information

CAS No. 622856-21-7
Masse moléculaire 468.33
Formule C₂₄H₁₉Cl₂N₃O₃
SMILES

O=C1NC(C2=C(C3=C(N4CCCNC)C=CC(O)=C3)C4=CC(C5=C(Cl)C=CC=C5Cl)=C21)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Parsels LA, et al. Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells. Mol Cancer Ther. 2009 Jan;8(1):45-54. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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PD-321852

Voir tous les produits spécifiques à Isoform Checkpoint Kinase (Chk)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

PD-321852 Related Classifications

HY-124731 Related Classifications