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Pivekimab

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Pivekimab is a human IgG1 monoclonal antibody that targets interleukin-3 (IL-3) and CD123. Pivekimab is used to synthesize pivekimab sunirine, a CD123-directed antibody-active molecule conjugate (ADC). Pivekimab is used in the study of blastic plasmacytoid dendritic cell neoplasm (BPDCN).

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  • Pureté: 97.19%
  • CAS No.: 2234335-84-1
  • Masse moléculaire:145.98 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Pivekimab
  • Experimental Validation Results for Pivekimab
  • Experimental Validation Results for Pivekimab
  • Pivekimab Chemical Structure
    Pivekimab Chemical Structure
CAS No.: 2234335-84-1
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Pivekimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human IL-3R alpha/CD123 Protein (ECD, His Tag) can bind Pivekimab. The EC50 for this effect is 6.14 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 THP-1 cells with Pivekimab (HY-P99234, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Pivekimab Chemical Structure
    1/16
  • Pivekimab
  • Immobilized Human IL-3R alpha/CD123 Protein (ECD, His Tag) can bind Pivekimab. The EC50 for this effect is 6.14 ng/mL.
  • Flow cytometric analysis of 1.5X106 THP-1 cells with Pivekimab (HY-P99234, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).