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Cat. No.: HY-126042S2

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(±)-Lisofylline-d₃

Name: (±)-Lisofylline-d3
Brand: MedChemExpress
SKU: HY-126042S2
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(Synonyms: (±)-Lisophylline-d₃)

(±)-Lisofylline-d₃ is the deuterium labeled (±)-Lisofylline. (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research.

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CAS No.: 1268605-96-4
Formule: C₁₃H₁₇D₃N₄O₃
Masse moléculaire:283.34

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(±)-Lisofylline-d₃ Chemical Structure

CAS No.: 1268605-96-4

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Activité biologique
- Description
- In Vitro
- Application
Chemical Information
Pureté et documentation
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Activité biologique

Description

(±)-Lisofylline-d₃ is the deuterium labeled (±)-Lisofylline^[1]. (±)-Lisofylline ((±)-Lisophylline) is the racemate of Lisofylline. Lisofylline inhibits the generation of phosphatidic acid and free fatty acids. Lisofylline also blocks the release of pro-inflammatory cytokines in oxidative tissue injury, in response to cancer chemotherapy and in experimental sepsis. Lisofylline can be used for Type 1 diabetes research^[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1268605-96-4
Unlabeled CAS 6493-06-7
Masse moléculaire 283.34
Formule C₁₃H₁₇D₃N₄O₃
SMILES

O=C(N1CCCCC(O)C)N(C)C2=C(N(C([2H])([2H])[2H])C=N2)C1=O
Synonyms

(±)-Lisophylline-d₃
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Yang Z, et al. Lisofylline: a potential lead for the treatment of diabetes. Biochem Pharmacol. 2005 Jan 1;69(1):1-5. [Content Brief]

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Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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- In Vitro
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Chemical Information
Pureté et documentation
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(±)-Lisofylline-d3