rel-(-)-Vesamicol
rel-(-)-Vesamicol (rel-(-)-AH5183) is the racemate of (-)-Vesamicol. (-)-Vesamicol is a vesicular acetylcholine transporter inhibitor. (-)-Vesamicol reversibly and non-competitively inhibits the transport of acetylcholine into circulating synaptic vesicles and blocks the activity of vesicular acetylcholine transporters in medial amygdala neurons. (-)-Vesamicol is applicable to research related to central precocious puberty.
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- CAS No.: 115362-28-2
- Formule: C17H25NO
- Masse moléculaire:259.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 115362-28-2
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Masse moléculaire 259.39
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Formule C17H25NO
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SMILES
O[C@H]1[C@H](N2CCC(C3=CC=CC=C3)CC2)CCCC1
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Synonyms
rel-(-)-AH5183
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Searl T, et al. Acetylcholine recycling and release at rat motor nerve terminals studied using (-)-vesamicol and troxpyrrolium. The Journal of physiology. 1991 Dec;444:99-116. [Content Brief]
[2]. Shen Y, et al. Early Exposure of an Infantile Rat to Sex-Related Content Induces Precocious Puberty by Activation of Cholinergic Neurons in the Amygdala and KNDy Neurons in the Arcuate Nucleus. ACS omega. 2025 Jul 22;10(28):30327-30334. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
rel-(-)-Vesamicol Related Classifications
HY-113995A Related Classifications
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- rel-(-)-Vesamicol
- 115362-28-2
- rel-(-)-AH5183
- mAChR
- immature female rats
- central precocious puberty
- miniature endplate current
- median eminence GnRH
- vesicular acetylcholine transporter
- synaptic vesicles
- arcuate nucleus kisspeptin
- medial amygdala neurons
- acetylcholine
- evoked endplate current
- Inhibitor
- inhibitor
- inhibit