country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-N1342

Copy Link Print Information

Rocaglaol

Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 147059-46-9
Formule: C₂₆H₂₆O₆
Masse moléculaire:434.48

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Rocaglaol Chemical Structure

CAS No.: 147059-46-9

Size

Prix

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	6 nM Compound: rac-1	Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 19655762]
HCT-15	IC₅₀	6 nM Compound: rac-1	Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay Cytotoxicity against human HCT15 cells after 72 hrs by MTS assay	[PMID: 19655762]
HepG2	IC₅₀	70 nM Compound: rac-1	Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay Cytotoxicity against human HepG2 cells after 72 hrs by MTS assay	[PMID: 19655762]
HL-60	IC₅₀	3 nM Compound: rac-1	Cytotoxicity against human HL60 cells after 72 hrs by MTS assay Cytotoxicity against human HL60 cells after 72 hrs by MTS assay	[PMID: 19655762]
HT-29	ED₅₀	0.0007 μM Compound: 9	Cytotoxicity against human HT-29 cells Cytotoxicity against human HT-29 cells	[PMID: 23301897]
HT-29	ED₅₀	0.7 nM Compound: 9	Cytotoxicity against human HT-29 cells Cytotoxicity against human HT-29 cells	[PMID: 23301897]
KB	IC₅₀	2 nM Compound: rac-1	Cytotoxicity against human KB cells after 72 hrs by MTS assay Cytotoxicity against human KB cells after 72 hrs by MTS assay	[PMID: 19655762]
Lewis lung carcinoma cell line	IC₅₀	0.034 μg/mL Compound: 2	Cytotoxicity against mouse LL/2 cells Cytotoxicity against mouse LL/2 cells	[PMID: 10785416]
MCF7	IC₅₀	4 nM Compound: rac-1	Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 19655762]
MCF7	IC₅₀	4 nM Compound: rac-1	Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells expressing P-glycoprotein after 72 hrs by MTS assay	[PMID: 19655762]
NIH3T3	IC₅₀	2 ng/mL Compound: 1	Growth inhibition of mouse NIH/3T3 cells Growth inhibition of mouse NIH/3T3 cells	[PMID: 8759160]
NIH3T3	IC₅₀	5.3 ng/mL Compound: 1	Growth inhibition of mouse NIH/3T3 cells expressing H-ras Growth inhibition of mouse NIH/3T3 cells expressing H-ras	[PMID: 8759160]
NIH3T3	IC₅₀	7 ng/mL Compound: 1	Growth inhibition of mouse NIH/3T3 cells expressing K-ras Growth inhibition of mouse NIH/3T3 cells expressing K-ras	[PMID: 8759160]
NIH3T3	IC₅₀	7.5 ng/mL Compound: 1	Growth inhibition of mouse NIH/3T3 cells expressing N-ras Growth inhibition of mouse NIH/3T3 cells expressing N-ras	[PMID: 8759160]
NRK	IC₅₀	10 ng/mL Compound: 1	Growth inhibition of rat NRK cells Growth inhibition of rat NRK cells	[PMID: 8759160]
NRK	IC₅₀	5.8 ng/mL Compound: 1	Growth inhibition of rat NRK cells expressing K-ras Growth inhibition of rat NRK cells expressing K-ras	[PMID: 8759160]
P388	IC₅₀	<0.01 μg/mL Compound: 2	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 10785416]
WEHI-164	IC₅₀	0.023 μg/mL Compound: 2	Cytotoxicity against mouse WEHI164 cells Cytotoxicity against mouse WEHI164 cells	[PMID: 10785416]

Chemical Information

CAS No. 147059-46-9
Masse moléculaire 434.48
Formule C₂₆H₂₆O₆
SMILES

O[C@@H]1C[C@@H](C2=CC=CC=C2)[C@]3(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C5[C@@]31O
Structure Classification
- Others
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Mi Q, et al. Rocaglaol induces apoptosis and cell cycle arrest in LNCaP cells. Anticancer Res. 2006;26(2A):947-952. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis