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Trontinemab

(Synonyms: RG6102; RO-7126209)
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Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human TFR1.

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  • Pureté: 99.93%
  • CAS No.: 2568868-35-7
  • Masse moléculaire:194.25 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Trontinemab
  • Experimental Validation Results for Trontinemab
  • Experimental Validation Results for Trontinemab
  • Experimental Validation Results for Trontinemab
  • Trontinemab Chemical Structure
    Trontinemab Chemical Structure
CAS No.: 2568868-35-7
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Trontinemab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG1-kappa-(Fab G1-kappa with domain crossover)

  • 1/16

    IgG1-kappa-(Fab G1-kappa with domain crossover)

  • 1/16

    Immobilized Human Beta-amyloid/Beta-APP Protein (hFc Tag) can bind Trontinemab. The EC50 for this effect is 34.64 ng/mL.

  • 1/16

    Immobilized HY-P71069 TFRC Protein, Human (HEK293, His) can bind Trontinemab. The EC50 for this effect is 193.5 ng/mL.

  • Trontinemab Chemical Structure
    1/16
  • Trontinemab
  • Immobilized Human Beta-amyloid/Beta-APP Protein (hFc Tag) can bind Trontinemab. The EC50 for this effect is 34.64 ng/mL.
  • Immobilized HY-P71069 TFRC Protein, Human (HEK293, His) can bind Trontinemab. The EC50 for this effect is 193.5 ng/mL.
  • IgG1-kappa-(Fab G1-kappa with domain crossover)
  • IgG1-kappa-(Fab G1-kappa with domain crossover)