YTH-IN-2
YTH-IN-2 is a YTH domain inhibitor of YTHDC2 with an IC50 of 16.84 μM. YTH-IN-2 can serve as a lead compound for discovering efficient, selective, and cell-active small-molecule inhibitors of YTHDC2.
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- CAS No.: 86886-76-2
- Formule: C14H12ClNO2
- Masse moléculaire:261.70
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
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YTHDC2 16.84 μM (IC50) |
YTH-IN-2 (H3) (30 min compound-protein incubation; 2 h post-probe addition incubation) inhibits recombinant human GST-tagged YTHDC2 YTH-domain protein binding to FAM-labeled m6A-mRNA with an IC50 of 16.84 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 86886-76-2
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Masse moléculaire 261.70
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Formule C14H12ClNO2
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SMILES
O=C(CC1=CC=CC=C1)NC2=CC(Cl)=CC=C2O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YTH-IN-2 Related Classifications
HY-181117 Related Classifications
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